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Due to a vast influx in the secretory phase of the menstrual cycle, leukocytes represent 40–50% of the decidua at the time of implantation. Their importance for the implantation, maintenance of pregnancy, and parturition are known yet not fully understood. Thus, in idiopathic infertility, decidual immune-related factors are speculated to be the cause. In this review, the immune cell functions in the decidua were summarized, and clinical diagnostics, as well as interventions, were discussed. There is a rising number of commercially available diagnostic tools. However, the intervention options are still limited and/or poorly studied. In order for us to make big steps towards the proper use of reproductive immunology findings, we need to understand the mechanisms and especially support translational research.

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𝗝𝘂𝗽𝗶𝘁𝗲𝗿 𝗘𝗱𝗴𝗲 𝗖𝗦𝗕 𝗕𝗮𝗻𝗸 𝗥𝘂𝗣𝗮𝘆 𝗟𝗶𝗳𝗲 𝗧𝗶𝗺𝗲 𝗙𝗿𝗲𝗲 𝗖𝗿𝗲𝗱𝗶𝘁 𝗖𝗮𝗿𝗱 𝗙𝘂𝗹𝗹 𝗗𝗲𝘁𝗮𝗶𝗹𝘀 & 𝗔𝗽𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻 𝗣𝗿𝗼𝗰𝗲𝘀𝘀 - Features - Jupiter Community

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