Pharmaceutics, Free Full-Text
Por um escritor misterioso
Last updated 05 julho 2024
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Chronic wound healing represents an impactful financial burden on healthcare systems. In this context, the use of natural products as an alternative therapy reduces costs and maintains effectiveness. Phytotherapeutic gels applied in photodynamic therapy (PDT) have been developed to act as topical healing medicines and antibiotics. The bioactive system is composed of Spirulina sp. (source of chlorophylls) and Copaifera reticulata oil microdroplets, both incorporated into a polymeric blend constituted by kappa-carrageenan (k-car) and F127 copolymer, constituting a system in which all components are bioactive agents. The flow behavior and viscoelasticity of the formulations were investigated. The photodynamic activity was accessed from studies of the inactivation of Staphylococcus aureus bacteria, the main pathogen of hospital relevance. Furthermore, in vivo studies were conducted using eighteen rabbits with dermatitis (grade III and IV) in both paws. The gels showed significant antibiotic potential in vitro, eliminating up to 100% of S. aureus colonies in the presence or absence of light. The k-car reduced 41% of the viable cells; however, its benefits were enhanced by adding chlorophyll and copaiba oil. The animals treated with the phytotherapeutic medicine showed a reduction in lesion size, with healing and re-epithelialization verified in the histological analyses. The animals submitted to PDT displayed noticeable improvement, indicating this therapy’s viability for ulcerative and infected wounds. This behavior was not observed in the iodine control treatment, which worsened the animals’ condition. Therefore, gel formulations were a viable alternative for future pharmaceutical applications, aiming at topical healing.
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Principles of pharmacoeconomic analysis – Center for International Research and Publishing in Pharmacy Practice
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Top view of colorful tablets and capsule pills in blister packaging arrange with beautiful pattern. Pharmaceutical industry concept. Full frame pills background. Global pharmaceuticals. Defective. 7774187 Stock Photo at Vecteezy
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Pharmaceutical Credit Card Flash Drive - 4 GB Memory with Logo
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Archem Process Equipment Ltd.
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The British Pharmaceutical Codex : Not Available : Free Download, Borrow, and Streaming : Internet Archive
Salivary concentrations and plasma protein binding of carbamazepine and carbamazepine 10,11-epoxide in epileptic patients. - Abstract - Europe PMC
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MXenes and MXene-based materials for removal of pharmaceutical compounds from wastewater: Critical review - ScienceDirect
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Dota 6.64 Ai Plus - Colaboratory
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Free Reference Letter For Pharmacy Technician - Download in Word, Google Docs, PDF, Apple Pages
Pharmaceutics : the science of dosage form design : Free Download, Borrow, and Streaming : Internet Archive
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Alembic Pharmakon 1965 - Albany College of Pharmacy and Health Sciences - New York Heritage Digital Collections
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PDF) Pharmacy and the EU : the impact of European Union membership on the pharmacy profession in Malta
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